China3D printingNet February 24th,3D printingThe start-up company Copper3D is located in Chile and the United States. It uses nano-copper additives and adds antibacterial properties to polymers such as PLA and TPU, thereby creating antibacterial properties.3D printingequipment. Last year, Copper3D worked with the National Aeronautics and Space Administration (NASA) to study microbial risks in space, but now the startup is working on an important project at home.
According to UNICEF data, the number of children and adolescents infected with HIV in 2017 reached 3 million, and 430,000 were newly infected.inThere are 130,000 deaths due to AIDS-related causes. The United Nations Programme on HIV/AIDS (UNAIDS) reported that 26,000 new HIV infections among children under the age of 14 in 2018 were caused by drug withdrawal and breastfeeding during pregnancy. The World Health Organization reported that by the end of 2018, there were still 37.9 million people living with HIV globally, and 8.1 million of them did not even know they had the disease.
Many companies and scientists around the world are working hard to use technology to help control dangerous bacteria and viruses with high replication rates, such as HIV. Copper3D uses copper nanotechnology to create a3D printingEquipment, the equipment can effectively kill the HIV virus on certain subjects under appropriate conditions.
Dr. Claudio Soto, Medical Director of Copper3D, said: “Understanding the global issues behind HIV statistics and analyzing the role of our antibacterial materials in curbing the spread of the HIV virus makes us think that we can develop a device that can work. It is like the interface between mother and child to prevent this virus from spreading through breastfeeding, which is one of the main ways of infection.
The original idea was based on the results of some existing studies. These studies showed that copper-based additives and filters can inactivate HIV virus in breast milk solution, especially for protease (essential for virus replication), while copper Ions degrade proteases non-specifically. The phospholipid membrane of the virus and its nucleic acid are denatured; however, several issues such as toxicity levels, nutritional degradation of milk, virus inactivation time or the optimal size/form of these filters remain unresolved. “
3D concept of virus inactivator (patent pending)
Copper3D, led by co-founders Martínez, Dr. Soto, and CEO Andrés Acuña, began to collaborate on a project. Last year, they filed a patent application for the project called “Breast Milk Shield Virus Inactivation System to Prevent the Transmission of HIV in Breast Milk.”First, the HIV-infected breast milk sample was used to test the virus inactivation effect of its PLACTIVE material, and then the research team designed an object that can be optimizedDuring breastfeedingmiddle” InactivateHIV virus” function.
“Our mission as a company has always been related to the impact of materials and nanotechnology innovations on the world. Research on active/antimicrobial medical devices and their applications is carried out with these studies, which makes us proud. We believe that we are We are in a leading position in the industry and awarded this honor with a high sense of responsibility. We will continue to apply innovation on the road and always consider playing an important role in the most pressing global healthcare challenges. Among these challenges, our antibacterial Materials, strict technical verification processes and laboratory certification can generate new categories that can avoid infection and save millions of lives worldwide.”
Virology Laboratory, Clinico University Hospital, Chile
The start-up company commissioned a proof-of-concept laboratory study at the Virology Laboratory of the University of Clinico in Chile to verify the potential HIV virus inactivation capabilities of PLACTIVE. The study used a split sample protocol to test and treat 20 HIV-1 sub-samples (type B, cultured from the C4CR4 co-receptor infectious clone NL4-3).
3D model of virus inactivator (patent pending)
China3D printingOnline reviews: These results are very encouraging. This provided support for the second phase of the research team’s work. The design of a device that expands the contact surface 10 times for use in HIV-contaminated milk. The device is embedded with nano-copper and can be used in breast milk. Use during feeding.Like any innovative project, this is an evolving process. We have learned a lot in this process, and in the future we will continue to design, iterate, test, verify and learn antimicrobial materials and devices. In the first phase of our research, the preliminary results obtained through virus inactivation of the active/antibacterial nanocomposite material provided us with a huge impetus to continue this research field. The second and final phase of the research will be in 2020 End of the second quarter of the year. “
China3D printingnetworkOriginal article!
(Editor in charge: admin)
0 Comments for “Copper3D develops antibacterial 3D printing device to try to reduce the spread of AIDS in breastfeeding”