First in Europe!Italy successfully completes 3D printed bronchial implant surgery

Because of the commonness of tracheal congenital diseases, infants cannot meet the treatment needs of all infants due to their physical condition, tracheal development, postoperative recovery, etc. At present, in order to better solve tracheal diseases, scientists have adopted
biology
3D printingMany attempts have been made in the way of the trachea.
It is reported that the University of Michigan at Ann Arbor
medicine
Dr. David A. Zopf and colleagues describe this transplant
Operation
. The transplanted baby suffers from local bronchomalacia, and the absorbable stent used in the operation is made of polycaprolactone.

The author pointed out that the baby boy named Kaiba Gionfriddo was born at 35 weeks of gestation. He appeared to be in good health, but he developed chest wall depression and difficulty breathing after 6 weeks. When this happens, it means that before 2 months of age, tracheal intubation is required to maintain ventilation. Therefore, they used a computer to design a model of a child’s tracheal stent. Using thermoplastic bioabsorbable materials, they fabricated a tracheal stent using laser sintering technology. In the transplant operation, the hole in the stent and the trachea are used for fixation. Seven days after the placement of the stent, the mechanical ventilator was gradually removed, and the ventilator support was completely stopped 21 days after the operation. A year later, the child’s left main bronchus was observed through endoscopic contrast surgery and found that everything was normal.

In 2017, a team of doctors from the CHU Hospital in Toulouse, France, have successfully3D printingThe customized tracheobronchial prosthesis is implanted in the patient’s body, setting the first in the world for the medical profession.It is reported that the
Implants
It was designed and manufactured in collaboration with Anatomik Modeling, a startup company based in Toulouse, which specializes in custom 3D implants.

It is reported that the patient who received the customized 3D implant was a 60-year-old patient who first received a lung transplant at Toulouse University Hospital two years ago. However, after the operation, the patient felt uncomfortable breathing and had difficulty breathing. During the examination, the doctor found that the patient’s bronchi was narrowed and contracted (called stenosis), which means that measures must be taken to treat it.

The doctor’s intervention is based on3D printingWith the help of manufacturing customized silicone tracheal bronchial prosthesis form. To make the implant, Anatomik Modeling collaborated with CHU to model the implant based on scanned patient bronchus data.Then, the 3D implant
Mould
quilt3D printing, Which allows casting silicone elastomer prostheses.

About three months ago, CHU doctors successfully implanted a customized tracheobronchial prosthesis into the patient’s body. After the operation, the patient recovered well, and the technology has successfully helped more than three patients, and will soon help two patients who are currently waiting for surgery.

3D printingTechnology allows French doctors to treat patients with customized bronchial implants, which helps avoid potential complications due to inappropriate implants and stents. Although the innovative 3D implant is still in the experimental stage, they plan to commercialize it in 2018. “Anatomik Modeling and CHU’s doctor said.

Currently,3D printingThe challenge for custom-made stents is their cost, because custom-fitted implants are better than their
standard
Chemical counterparts are expensive.Nevertheless, the 3D tracheobronchial prosthesis
clinical
The test is still in progress.

According to a report by the European Network, citing the European Union News Agency, an Italian hospital recently performed bronchomalacia and severe bronchial wall atrophy surgery for a 5-year-old child. The hospital used it for the first time.3D printingThe bronchial implantation operation was successful.Experts say that implementing for patients3D printingBronchial implant surgery is the first in Italy and Europe.

According to reports, implanted for patients3D printingBronchus, designed by Rome Jesus Children’s Hospital and commissioned by Prosilas, Italy3D printingCenter for printing. The project uses the most advanced imaging and bioengineering technologies.
Experts say that in3D printingBefore bronchial implant surgery, the doctor3D printingThe bronchus that has been taken out has undergone a low-temperature sterilization treatment to prevent it from changing its structure and characteristics.At the same time, the hospital has also cooperated with the University of Modena and the University of Reggio Emilia.3D printingThe bronchus was tested for mechanical resistance.

According to reports, the
Medical treatment
The medical team and experts spent 6 months of preparation time from the design to the implementation of the procedure.Rome Jesus Children’s Hospital stated that this time3D printingThe bronchial implant operation takes up to 8 hours. Because the bronchi of young children is compressed between the left pulmonary artery and the aorta, the operation becomes very difficult. Long-term bronchial compression narrows the patient’s airway and causes breathing difficulties. Before the operation, the patient can only breathe with the help of medical equipment.

(Editor in charge: admin)