China3D printingNet, April 7th, funded by the U.S. National Defense Health Program, 4D Bioprinting, Biomanufacturing and Biomanufacturing (4D Bio3) is a collaboration between the Uniformed Service University of Health Sciences (USUHS) and the Geneva Foundation, a non-profit organization that promotes military medical research. Cooperation between. The plan promotes the application and development of bio-manufacturing and bio-printing technologies for research in accordance with the priorities of the U.S. Department of Defense. 4D Bio3 is also involved in medical research in outer space.
4D Bio3 is currently working with the Foundation, Safi Biosolutions, Advanced Bioprocess Services, Massachusetts General Hospital and Florida3D printingSciperio, the research arm of the company nScrypt, collaborates to make human blood on demand. Yes, you’re not mistaken.
Through USUHS, the US Department of Defense and the Geneva Foundation established the 4D Bio3 blood on-demand program to provide fresh, uncontaminated blood supplies to military service personnel around the world. The goal of the current partnership with Sciperio is to create solutions for the blood supply of the future, and the production of human blood on demand seems to be the best way.
The company and Safi Biosolutions received a joint award of US$8.8 million to fund their contribution to the program in the first year. The overall goal of the first year of the program is to create a “whole blood development roadmap”, and Sciperio’s part will be the development of a robust automated bioreactor that can provide real-time control and feedback through multiple sensors. Sciperio derivative product nScrypt will design and manufacture award-winning high-precision next-generation micro-dispensing and3D printingSystem, it will build a bioreactor.
Explains Dr. Ken Church, CEO of Sciperio and nScrypt“How do you make blood related to patient use? We are using several nScrypt SmartPump tool heads to precisely micro-distribute growth promoters in the bioreactor, thereby causing cell expansion and differentiation. There are many interesting things about bio-manufacturing blood. Aspects and advantages, including the ultimate benefit to humans. Starting from a small number of cells, our bioreactor will produce billions of cells, which is a necessary condition for patients with blood transfusion. We believe that this exciting project will have an angel. Stable access to safe, affordable blood on-demand where and when it is needed.”
The nScrypt SmartPump micro-distribution tool head can handle more than 10,000 commercially available materials and is the most extensive of any micro-distribution system. According to nScrypt, SmartPump’s nib is only 10 microns, which is the smallest usable diameter on the commercial market.
If the project is successful and the team can produce human red blood cells that are safe for human blood transfusion on site, then there will be less attention to donor blood screening. This solution may mean that there is no need for extensive blood donors, which can help simplify the logistics of blood transportation, processing, and long-term storage. This is especially useful for military personnel in remote areas.
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